Human B7H3 Protein

产品名称	Human B7H3 Protein
产品货号	DTD0638
产品规格
价格

产品详情

名称	Human B7H3 Protein
宿主细胞	HEK293
纯度	>95% by SDS-PAGE; >90% by HPLC
基因名	CD276
物种	Human
标签	His
缓冲液	1×PBS，pH7.4
储存方式	For long term use, aliquot and store at -80°C (avoiding multiple freeze-thaws).
SDS-PAGE
HPLC
ELISA

产品说明书
产品说明书

B7-H3 (also known as CD276) is a member of the B7 superfamily of immunoregulatory proteins. It is a type I transmembrane glycoprotein that is expressed in various human tissues and upregulated in numerous cancers, including lung, breast, prostate, and colorectal tumors. B7-H3 plays a complex role in immune modulation and has been shown to both stimulate and inhibit T cell responses depending on the context. Recent studies suggest that B7-H3 contributes to tumor immune evasion, angiogenesis, and metastasis, making it a promising target for cancer immunotherapy. Due to its restricted expression in normal tissues and high expression in tumors, B7-H3 is being actively investigated in antibody-drug conjugates (ADCs), CAR-T therapies.

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发货时间：确认订单并完成付款后1~2个工作日内安排发货。
发货方式：冰袋或干冰。