ÑòÍÕµÈÂæÍտƶ¯ÎïÌåÄÚ³ýÁËÌìÈ»´æÔÚȱʧÇáÁ´¼°ÖØÁ´CH1½á¹¹µÄÖØÁ´¿¹Ì壨HCAb£©£¬Ò²´æÔÚÓÉÁ½ÌõÖØÁ´ÓëÁ½ÌõÇáÁ´×é³ÉµÄIgGͬÖÖÐÍ¿¹Ì壬¼´ÍÕ¿ÆIgG1¡£
µÂÌ©ÉúÎïÌṩÑòÍÕIgG1 SingleB?¿ìËÙ·¢ÏÖ·þÎñ£¬´ÓÃâÒßµ½µ¥¿¹¿ìÖÁ90Ì죻ӵÓÐ×Ô½¨ÑòÍÕÑøÖ³»ùµØ£¬±£Ö¤ÏîĿʹÓÃδ¾ÃâÒßÑòÍÕ£»¿¹Ìå·¢ÏÖÎÞÐè·±ËöµÄ½¨¿âÁ÷³Ì£¬Ö±½Ó¶ÔÑòÍÕBϸ°û½øÐÐɸѡ£»¿¹ÌåÌåÄÚÌìÈ»³ÉÊì£¬ÖØÇáÁ´ÌìÈ»Åä¶Ô£¬¸üºÃµÄ±£ÁôÁË¿¹ÌåÇ׺ÍÁ¦¡£
ÌìÈ»³ÉÊì
ÖØÇáÁ´ÌìÈ»Åä¶Ô
ÌåÄÚ³ÉÊì
90Ìì¸ß½»¸¶
½»¸¶50ÖêFACS binder
¼°¿¹ÌåÐòÁÐ
¡°1+1¡±Ë«±£ÕÏ
¼ÇÒäBϸ°û&½¬Ï¸°û
˫ɸѡ˫±£ÕÏ
È«Ãæ¼ì²â
FACS Binding/Blocking
Affinity Ranking
½×¶Î | ·þÎñÄÚÈÝ | ÖÜÆÚ | ½»¸¶ |
---|---|---|---|
½×¶Î¢ñ ¶¯ÎïÃâÒß |
|
8~9ÖÜ |
Premium Package
Economic Package
|
½×¶Î¢ò ¡°1+1¡±Ë«É¸Ñ¡ |
|
1Ìì | |
½×¶Î¢ó BGE?¸ßͨÁ¿±í´ï¼°¹¦ÄÜÑéÖ¤ |
|
1~2ÖÜ | |
½×¶Î¢ô ÄÉÃ׿¹Ìå»ùÒò²âÐò |
|
1ÖÜ | |
½×¶Î¢õ ÖØ×鿹Ìå±í´ïÓë´¿»¯£¨¿ÉÑ¡£© |
|
Ïêѯ |
CDR3ÇøÊǾö¶¨½áºÏ¿¹ÌåÇ׺ÍÁ¦ºÍÌØÒìÐÔµÄÖ÷µ¼ÇøÓò¡£ÂæÍտƶ¯ÎïIgG¿¹ÌåµÄÖØÁ´CDR3ÇøÒ»°ãÓÉ12~17¸ö°±»ùËá²Ð»ù×é³É£¬¶øÈË»òСÊóµÄÖØÁ´CDR3ÇøÒ»°ãÓÉ9~12¸ö°±»ùËá²Ð»ù×é³É¡£¸ü³¤µÄCDR3ÇøÒ×ÓÚÐγÉ͹»·½á¹¹£¬²åÈë¶ÔÓ¦¿¹Ô·Ö×ӵŵ²Û»òÁÑ϶ÄÚ£¬ÓÐÀûÓÚÐγɿ¹Ô½áºÏ½çÃæ»ò»¥²¹Î»£¬Ôö´óÓ뿹ԵÄÏ໥×÷ÓÃÃæ»ý£¬´Ó¶ø²úÉúÁ˸ü¶à¿¹ÔÌØÒìÐÔ½áºÏ»ú»á¡£
Fig1 ÂæÍտƶ¯ÎÉÏ£©¡¢Ð¡Êó¡¢ÈË£¨Ï£©CDR3°±»ùËá²Ð»ùÊýÁ¿¶Ô±È
ÂæÍÕ¿ÆIGHV¿ò¼ÜÇøÐòÁÐÓëÈËÏàÓ¦¼Ò×å¿ò¼ÜÇøµÄÏàËÆ¶ÈÔÚ77%~95%Ö®¼ä£¬IGLV¿ò¼ÜÇøµÄÏàËÆ¶ÈÔÚ61%~91%Ö®¼ä£¬IGKV¿ò¼ÜÇøµÄÏàËÆ¶ÈÔÚ60%~85%Ö®¼ä¡£ÓëÈËÀ࿹ÌåVÇø¿ò¼ÜÇø»ùÒòÖ®¼äµÄÕâÖָ߶ÈÐòÁм°½á¹¹ÏàËÆÐÔÔÚÃâÒßÔÐÔ·½ÃæÕ¹ÏÖ³öÖØÒªÓÅÊÆ¡£
Fig2 ÂæÍտƶ¯ÎïIGHV¿ò¼ÜÇøÓëÈË¿¹ÏàËÆ¶È±È¶Ô